2HVL
Crystal structure of the HePTP catalytic domain C270S mutant
Summary for 2HVL
Entry DOI | 10.2210/pdb2hvl/pdb |
Related | 1ZC0 2GPO |
Descriptor | Tyrosine-protein phosphatase non-receptor type 7, PHOSPHATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | heptp, human tyrosine phosphatase catalytic domain, lc-ptp, ptpn7, substrate-trapping mutant, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P35236 |
Total number of polymer chains | 1 |
Total formula weight | 35601.96 |
Authors | Page, R.,Critton, D.,Ragusa, M. (deposition date: 2006-07-29, release date: 2007-08-07, Last modification date: 2024-02-14) |
Primary citation | Critton, D.A.,Tortajada, A.,Stetson, G.,Peti, W.,Page, R. Structural basis of substrate recognition by hematopoietic tyrosine phosphatase Biochemistry, 47:13336-13345, 2008 Cited by PubMed: 19053285DOI: 10.1021/bi801724n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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