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2HVL

Crystal structure of the HePTP catalytic domain C270S mutant

Summary for 2HVL
Entry DOI10.2210/pdb2hvl/pdb
Related1ZC0 2GPO
DescriptorTyrosine-protein phosphatase non-receptor type 7, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsheptp, human tyrosine phosphatase catalytic domain, lc-ptp, ptpn7, substrate-trapping mutant, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P35236
Total number of polymer chains1
Total formula weight35601.96
Authors
Page, R.,Critton, D.,Ragusa, M. (deposition date: 2006-07-29, release date: 2007-08-07, Last modification date: 2024-02-14)
Primary citationCritton, D.A.,Tortajada, A.,Stetson, G.,Peti, W.,Page, R.
Structural basis of substrate recognition by hematopoietic tyrosine phosphatase
Biochemistry, 47:13336-13345, 2008
Cited by
PubMed: 19053285
DOI: 10.1021/bi801724n
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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