3KHJ

C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64

Summary for 3KHJ

• Entry DOI: 10.2210/pdb3khj/pdb
• Related: 1LRT 1NF7 1NFB 1PVN 1ZFJ
• Descriptor: Inosine-5-monophosphate dehydrogenase, INOSINIC ACID, N-(4-bromophenyl)-2-[2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]acetamide, ... (5 entities in total)
• Functional Keywords: enzyme-inhibitor complex, oxidoreductase
• Biological source: Cryptosporidium parvum; More
• Total number of polymer chains: 8
• Total formula weight: 312216.09

Authors

MacPherson, I.S.,Hedstrom, L.K. (deposition date: 2009-10-30, release date: 2010-02-02, Last modification date: 2024-02-21)

• Primary citation: Macpherson, I.S.,Kirubakaran, S.,Gorla, S.K.,Riera, T.V.,D'Aquino, J.A.,Zhang, M.,Cuny, G.D.,Hedstrom, L.; The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity.; J.Am.Chem.Soc., 132:1230-1231, 2010; PubMed: 20052976; DOI: 10.1021/ja909947a

Experimental method

X-RAY DIFFRACTION (2.8 Å)