3KHJ

C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Inosine-5-monophosphate dehydrogenase	polymer	361	38516.4	8	UniProt (Q5CPK7) Pfam (PF00478)	Cryptosporidium parvum	IMPDH
2	I, J, L, M, P... (A, B, C, D, E...)	INOSINIC ACID	non-polymer		348.2	8	Chemie (IMP)
3	K, O, T (B, D, H)	N-(4-bromophenyl)-2-[2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]acetamide	non-polymer		413.3	3	Chemie (C64)
4	N (D)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	AA, BA, U, V, W... (G, H, A, B, C...)	water	water		18.0	208	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 89 (UniProt: Q5CPK7)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

A, B, C, D, E, F, G, H: 135 - 400 (UniProt: Q5CPK7)

PDB	External Database	Details
Ser 90	-	linker
Gly 91	-	linker
Gly 92	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	308131.5
Non-Polymers*	Number of molecules	12
	Total formula weight	4084.6
All*	Total formula weight	312216.1

*Water molecules are not included.