3KHJ
C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Inosine-5-monophosphate dehydrogenase | polymer | 361 | 38516.4 | 8 | UniProt (Q5CPK7) Pfam (PF00478) | Cryptosporidium parvum | IMPDH |
| 2 | I, J, L, M, P... (A, B, C, D, E...) | INOSINIC ACID | non-polymer | 348.2 | 8 | Chemie (IMP) PubChem (135398640) PubChem (135486133) PubChem (137168789) PubChem (174152734) PubChem (135402036) PubChem (135449337) PubChem (135464200) PubChem (135530792) PubChem (135533971) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137257909) PubChem (138454308) PubChem (162510533) | |||
| 3 | K, O, T (B, D, H) | N-(4-bromophenyl)-2-[2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]acetamide | non-polymer | 413.3 | 3 | Chemie (C64) PubChem (44602364) | |||
| 4 | N (D) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 5 | AA, BA, U, V, W... (G, H, A, B, C...) | water | water | 18.0 | 208 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 89 (UniProt: Q5CPK7)
A, B, C, D, E, F, G, H: 135 - 400 (UniProt: Q5CPK7)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 90 | - | linker |
| Gly 91 | - | linker |
| Gly 92 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 308131.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4084.6 | |
| All* | Total formula weight | 312216.1 |
