Structure of the 80S mammalian ribosome bound to eEF2

This is a large structure.
Replaces:  3J74

Summary for 3J7P

Related3J7O 3J7Q 3J7R
Integrates4W21 4W22 4W23
EMDB information2644 2646 2649 2650
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (84 entities in total)
Functional Keywordsmammalian, sec61, translocation, translation, eef2, ribosome
Biological sourceSus scrofa (pig)
Total number of polymer chains82
Total molecular weight3407321.38
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.W.,Hegde, R.S. (deposition date: 2014-08-01, release date: 2014-09-03, Last modification date: 2018-07-18)
Primary citation
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.,Hegde, R.S.
Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157:1632-1643, 2014
PubMed: 24930395 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2014.05.024
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone615.4%20.1%0.28MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report