3H7H

Crystal structure of the human transcription elongation factor DSIF, hSpt4/hSpt5 (176-273)

Summary for 3H7H

• Entry DOI: 10.2210/pdb3h7h/pdb
• Related: 2EXU
• Descriptor: Transcription elongation factor SPT4, Transcription elongation factor SPT5, BETA-MERCAPTOETHANOL, ... (5 entities in total)
• Functional Keywords: helices surrounding beta sheet, transcription, activator, metal-binding, nucleus, repressor, transcription regulation, zinc-finger, methylation, phosphoprotein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P63272 O00267
• Total number of polymer chains: 2
• Total formula weight: 25493.84

Authors

Wenzel, S.,Wohrl, B.M.,Rosch, P.,Martins, B.M. (deposition date: 2009-04-27, release date: 2009-12-08, Last modification date: 2024-03-20)

• Primary citation: Wenzel, S.,Martins, B.M.,Rosch, P.,Wohrl, B.M.; Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface; Biochem.J., 425:373-380, 2010; PubMed: 19860741; DOI: 10.1042/BJ20091422

Experimental method

X-RAY DIFFRACTION (1.55 Å)