3H7H
Crystal structure of the human transcription elongation factor DSIF, hSpt4/hSpt5 (176-273)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transcription elongation factor SPT4 | polymer | 120 | 13395.4 | 1 | UniProt (P63272) Pfam (PF06093) In PDB | Homo sapiens (human) | hSPT4, DRB sensitivity-inducing factor small subunit, DSIF small subunit, DSIF p14 |
2 | B | Transcription elongation factor SPT5 | polymer | 106 | 11954.9 | 1 | UniProt (O00267) Pfam (PF03439) In PDB | Homo sapiens (human) | hSPT5, DRB sensitivity-inducing factor large subunit, DSIF large subunit, DSIF p160, Tat-cotransactivator 1 protein, Tat-CT1 protein |
3 | A | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A: 2 - 117 (UniProt: P63272)
B: 176 - 273 (UniProt: O00267)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ala -1 | - | expression tag |
Met 0 | - | expression tag |
Gly 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 172 | - | expression tag |
Ser 173 | - | expression tag |
His 174 | - | expression tag |
Met 175 | - | expression tag |
Gly 274 | - | expression tag |
Ser 275 | - | expression tag |
Gly 276 | - | expression tag |
Cys 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 25350.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 143.5 | |
All* | Total formula weight | 25493.8 |