3EJP

Golgi alpha-Mannosidase II in complex with 5-substituted swainsonine analog: (5R)-5-[2'-oxo-2'-(phenyl)ethyl]-swainsonine

Summary for 3EJP

Related1HTY 1HWW 1HXK 1PS2 1QWN 1R33 1R34 1TQV 2ALW 2F7O 2F7P 2F7Q 2F7R 2FYV 3BUB 3BUP 3CZN 3EJQ 3EJR 3EJS 3EJT 3EJU
DescriptorAlpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ... (6 entities in total)
Functional Keywordsgh38 glycosidase, glycosidase, golgi apparatus, hydrolase, membrane, metal-binding, signal-anchor, transmembrane
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains1
Total molecular weight120397.75
Authors
Kuntz, D.A.,Rose, D.R. (deposition date: 2008-09-18, release date: 2009-10-13, Last modification date: 2019-07-24)
Primary citation
Kuntz, D.A.,Nakayama, S.,Shea, K.,Hori, H.,Uto, Y.,Nagasawa, H.,Rose, D.R.
Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II.
Chembiochem, 11:673-680, 2010
PubMed: 20209559 (PDB entries with the same primary citation)
DOI: 10.1002/cbic.200900750
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.32 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1533 0.2% 0.8% 5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution