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3EJP

Golgi alpha-Mannosidase II in complex with 5-substituted swainsonine analog: (5R)-5-[2'-oxo-2'-(phenyl)ethyl]-swainsonine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAlpha-mannosidase 2polymer1045119701.61UniProt (Q24451)
Pfam (PF01074)
Pfam (PF09261)
Pfam (PF21260)
Pfam (PF07748)
Pfam (PF18230)
In PDB
Drosophila melanogaster (Fruit fly)Alpha-mannosidase II, AMAN II, MAN II, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, Golgi alpha-mannosidase II
2A2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
3AZINC IONnon-polymer65.41Chemie (ZN)
4A(4R)-2-METHYLPENTANE-2,4-DIOLnon-polymer118.21Chemie (MRD)
5A1-phenyl-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanonenon-polymer291.31Chemie (HN2)
6waterwater18.01295Chemie (HOH)
Sequence modifications
A: 13 - 1045 (UniProt: Q24451)
PDBExternal DatabaseDetails
Arg 1-expression tag
Ser 2-expression tag
Ser 3-expression tag
His 4-expression tag
His 5-expression tag
His 6-expression tag
His 7-expression tag
His 8-expression tag
His 9-expression tag
Gly 10-expression tag
Glu 11-expression tag
Phe 12-expression tag
Lys 907Glu 970SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight119701.6
Non-Polymers*Number of molecules4
Total formula weight696.1
All*Total formula weight120397.8
*Water molecules are not included.

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PDB entries from 2024-03-27

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