1R33

Golgi alpha-mannosidase II complex with 5-thio-D-mannopyranosylamine

Summary for 1R33

• Entry DOI: 10.2210/pdb1r33/pdb
• Related: 1HTY 1HWW 1HXK 1PS3 1QWN 1QWU 1QX1
• Descriptor: putative golgi alpha-mannosidase II, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
• Functional Keywords: glycosyl hydrolase family 38, hydrolase
• Biological source: Drosophila melanogaster (fruit fly)
• Total number of polymer chains: 1
• Total formula weight: 120301.64

Authors

Kuntz, D.A.,Xin, W.,Kavelekar, L.M.,Rose, D.R.,Pinto, B.M. (deposition date: 2003-09-30, release date: 2004-11-02, Last modification date: 2023-08-23)

• Primary citation: Kavelekar, L.M.,Kuntz, D.A.,Xin, W.,Johnston, B.D.,Svensson, B.,Rose, D.R.,Pinto, B.M.; 5-Thio-d-glycopyranosylamines and their amidinium salts as potential transition-state mimics of glycosyl hydrolases: synthesis, enzyme inhibitory activities, X-ray crystallography, and molecular modeling; TETRAHEDRON ASYMMETRY, 16:1035-1046, 2005; DOI: 10.1016/j.tetasy.2005.01.021

Experimental method

X-RAY DIFFRACTION (1.8 Å)