Golgi alpha-mannosidase II complex with 5-thio-D-mannopyranosylamine

Summary for 1R33

Related1HTY 1HWW 1HXK 1PS3 1QWN 1QWU 1QX1
Descriptorputative golgi alpha-mannosidase II, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
Functional Keywordsglycosyl hydrolase family 38, hydrolase
Biological sourceDrosophila melanogaster (fruit fly)
Total number of polymer chains1
Total molecular weight120301.64
Kuntz, D.A.,Xin, W.,Kavelekar, L.M.,Rose, D.R.,Pinto, B.M. (deposition date: 2003-09-30, release date: 2004-11-02, Last modification date: 2020-07-29)
Primary citation
Kavelekar, L.M.,Kuntz, D.A.,Xin, W.,Johnston, B.D.,Svensson, B.,Rose, D.R.,Pinto, B.M.
5-Thio-d-glycopyranosylamines and their amidinium salts as potential transition-state mimics of glycosyl hydrolases: synthesis, enzyme inhibitory activities, X-ray crystallography, and molecular modeling
TETRAHEDRON ASYMMETRY, 16:1035-1046, 2005
DOI: 10.1016/j.tetasy.2005.01.021
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1784 0.4% 0.9% 2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28