Golgi alpha-mannosidase II complex with 5-thio-D-mannopyranosylamine

Summary for 1R33

Related1HTY 1HWW 1HXK 1PS3 1QWN 1QWU 1QX1
Descriptorputative golgi alpha-mannosidase II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ... (6 entities in total)
Functional Keywordsglycosyl hydrolase family 38, hydrolase
Biological sourceDrosophila melanogaster (fruit fly)
Cellular locationGolgi apparatus membrane; Single-pass type II membrane protein Q24451
Total number of polymer chains1
Total molecular weight120301.64
Kuntz, D.A.,Xin, W.,Kavelekar, L.M.,Rose, D.R.,Pinto, B.M. (deposition date: 2003-09-30, release date: 2004-11-02, Last modification date: 2011-07-13)
Primary citation
Kavelekar, L.M.,Kuntz, D.A.,Xin, W.,Johnston, B.D.,Svensson, B.,Rose, D.R.,Pinto, B.M.
5-Thio-d-glycopyranosylamines and their amidinium salts as potential transition-state mimics of glycosyl hydrolases: synthesis, enzyme inhibitory activities, X-ray crystallography, and molecular modeling
TETRAHEDRON ASYMMETRY, 16:1035-1046, 2005
DOI: 10.1016/j.tetasy.2005.01.021
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.18540.4%0.9%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution