1PS3

Golgi alpha-mannosidase II in complex with kifunensine

Summary for 1PS3

Entry DOI	10.2210/pdb1ps3/pdb
Related	1HTY 1HWW 1HXK
Descriptor	Alpha-mannosidase II, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
Functional Keywords	glycosyl hydrolase, mannosidase, n-terminal alpha-beta domain, three helix bundle, 2 c-terminal beta barrels, hydrolase
Biological source	Drosophila melanogaster (fruit fly)
Total number of polymer chains	1
Total formula weight	120230.63
Authors	Shah, N.,Kuntz, D.A.,Rose, D.R. (deposition date: 2003-06-20, release date: 2003-12-16, Last modification date: 2023-08-16)
Primary citation	Shah, N.,Kuntz, D.A.,Rose, D.R. Comparison of Kifunensine and 1-Deoxymannojirimycin Binding to Class I and II alpha-Mannosidases Demonstrates Different Saccharide Distortions in Inverting and Retaining Catalytic Mechanisms Biochemistry, 42:13812-13816, 2003 Cited by PubMed: 14636047 DOI: 10.1021/bi034742r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation