1HWW

GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SWAINSONINE

Summary for 1HWW

Related1HTY
DescriptorALPHA-MANNOSIDASE II, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
Functional Keywordsn-terminal alpha-beta domain, three helix bundle, 2 c-terminal beta barrels, hydrolase
Biological sourceDrosophila melanogaster (fruit fly)
Total number of polymer chains1
Total molecular weight116800.79
Authors
van den Elsen, J.M.H.,Kuntz, D.A.,Rose, D.R. (deposition date: 2001-01-10, release date: 2002-01-10, Last modification date: 2020-07-29)
Primary citation
van den Elsen, J.M.,Kuntz, D.A.,Rose, D.R.
Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20:3008-3017, 2001
PubMed: 11406577 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/20.12.3008
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.87 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20510 0.4% 1.0% 2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02