3BUP

Golgi alpha-mannosidase II D341N acid-base catalyst mutant with bound mannose

Summary for 3BUP

Entry DOI	10.2210/pdb3bup/pdb
Related	1HTY 1HWW 1HXK 1PS2 1QWN 1QWU 1QX1 1R33 1R34 1TQS 1TQT 1TQU 1TQV 1TQW 2ALW 2F18 2F1A 2F1B 2F7O 2F7P 2F7Q 2F7R 3BUB 3BUD 3BUI 3BUQ
Descriptor	Alpha-mannosidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (6 entities in total)
Functional Keywords	glycosyl hydrolase family 38, glycosidase, golgi apparatus, membrane, signal-anchor, transmembrane, hydrolase
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	1
Total formula weight	120285.58
Authors	Kuntz, D.A.,Rose, D.R. (deposition date: 2008-01-03, release date: 2008-07-01, Last modification date: 2023-08-30)
Primary citation	Zhong, W.,Kuntz, D.A.,Ember, B.,Singh, H.,Moremen, K.W.,Rose, D.R.,Boons, G.J. Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. J.Am.Chem.Soc., 130:8975-8983, 2008 Cited by PubMed: 18558690 DOI: 10.1021/ja711248y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation