Golgi alpha-mannosidase II D341N acid-base catalyst mutant with bound mannose

Summary for 3BUP

Related1HTY 1HWW 1HXK 1PS2 1QWN 1QWU 1QX1 1R33 1R34 1TQS 1TQT 1TQU 1TQV 1TQW 2ALW 2F18 2F1A 2F1B 2F7O 2F7P 2F7Q 2F7R 3BUB 3BUD 3BUI 3BUQ
DescriptorAlpha-mannosidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (6 entities in total)
Functional Keywordsglycosyl hydrolase family 38, glycosidase, golgi apparatus, membrane, signal-anchor, transmembrane, hydrolase
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains1
Total molecular weight120285.58
Kuntz, D.A.,Rose, D.R. (deposition date: 2008-01-03, release date: 2008-07-01, Last modification date: 2020-07-29)
Primary citation
Zhong, W.,Kuntz, D.A.,Ember, B.,Singh, H.,Moremen, K.W.,Rose, D.R.,Boons, G.J.
Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.
J.Am.Chem.Soc., 130:8975-8983, 2008
PubMed: 18558690 (PDB entries with the same primary citation)
DOI: 10.1021/ja711248y
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1644 0.2% 1.1% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28