3D52

GOLGI MANNOSIDASE II complex with an N-aryl carbamate derivative of gluco-hydroxyiminolactam

Summary for 3D52

Entry DOI	10.2210/pdb3d52/pdb
Related	1HTY 1HWW 1HXK 1PS2 1QWN 1QWU 1QX1 1R33 1R34 2ALW 2F7O 2F7P 2F7Q 2F7R 3BUB 3BUD 3BUI 3BUP 3BUQ 3BVT 3BVU 3BVV 3BVW 3BVX 3CV5 3CZN 3CZS 3D4Y 3D4Z 3D50 3D51
Descriptor	Alpha-mannosidase 2, ZINC ION, (4R)-2-METHYLPENTANE-2,4-DIOL, ... (5 entities in total)
Functional Keywords	gh38 glycosidase, golgi apparatus, hydrolase, membrane, metal-binding, signal-anchor, transmembrane, zinc
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	1
Total formula weight	120230.94
Authors	Kuntz, D.A.,Tarling, C.A.,Withers, S.G.,Rose, D.R. (deposition date: 2008-05-15, release date: 2008-08-05, Last modification date: 2019-07-24)
Primary citation	Kuntz, D.A.,Tarling, C.A.,Withers, S.G.,Rose, D.R. Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen. Biochemistry, 47:10058-10068, 2008 Cited by PubMed: 18759458 DOI: 10.1021/bi8010785 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation