2YGE
E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin
Summary for 2YGE
Entry DOI | 10.2210/pdb2yge/pdb |
Related | 1A4H 1AH6 1AH8 1AM1 1AMW 1BGQ 1HK7 1US7 1USU 1USV 1ZW9 1ZWH 2AKP 2BRC 2BRE 2CG9 2CGE 2CGF 2IWS 2IWU 2IWX 2VW5 2VWC 2WEP 2WEQ 2WER 2XD6 2XX2 2XX4 2XX5 2YGA 2YGF |
Descriptor | ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN, GLYCEROL, ... (4 entities in total) |
Functional Keywords | chaperone |
Biological source | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) |
Cellular location | Cytoplasm: P02829 |
Total number of polymer chains | 1 |
Total formula weight | 25539.07 |
Authors | Roe, M.,Prodromou, C.,Pearl, L.H. (deposition date: 2011-04-14, release date: 2011-11-16, Last modification date: 2024-05-01) |
Primary citation | Millson, S.H.,Chua, C.S.,Solovieva, S.,Roe, M.,Polier, S.,Pearl, L.H.,Sim, T.S.,Prodromou, C.,Piper, P.W. Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise by Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25:3828-, 2011 Cited by PubMed: 21778327DOI: 10.1096/FJ.11-188821 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.956 Å) |
Structure validation
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