2YGA
E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin
Summary for 2YGA
Entry DOI | 10.2210/pdb2yga/pdb |
Related | 1A4H 1AH6 1AH8 1AM1 1AMW 1BGQ 1HK7 1US7 1USU 1USV 1ZW9 1ZWH 2AKP 2BRC 2BRE 2CG9 2CGE 2CGF 2IWS 2IWU 2IWX 2VW5 2VWC 2WEP 2WEQ 2WER 2XD6 2XX2 2XX4 2XX5 |
Descriptor | ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN (3 entities in total) |
Functional Keywords | chaperone |
Biological source | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) |
Cellular location | Cytoplasm: P02829 |
Total number of polymer chains | 1 |
Total formula weight | 25361.03 |
Authors | Roe, S.M.,Prodromou, C.,Pearl, L.H. (deposition date: 2011-04-12, release date: 2011-11-16, Last modification date: 2024-05-01) |
Primary citation | Millson, S.H.,Chua, C.,Roe, S.M.,Polier, S.,Solovieva, S.,Pearl, L.H.,Sim, T.,Prodromou, C.,Piper, P.W. Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise with Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25:3828-, 2011 Cited by PubMed: 21778327DOI: 10.1096/FJ.11-188821 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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