2YCW

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CARAZOLOL

2YCW の概要

• エントリーDOI: 10.2210/pdb2ycw/pdb
• 関連するPDBエントリー: 1DEP 2VT4 2Y00 2Y01 2Y02 2Y03 2Y04 2YCX 2YCY 2YCZ
• 分子名称: BETA-1 ADRENERGIC RECEPTOR, (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, HEGA-10, ... (4 entities in total)
• 機能のキーワード: gpcr, receptor, transducer, antagonist bound form, integral membrane protein, g-protein coupled receptor, thermostabilising point mutations, seven-helix receptor, 7tm receptor
• 由来する生物種: MELEAGRIS GALLOPAVO (TURKEY)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74045.38

構造登録者

Moukhametzianov, R.,Warne, T.,Edwards, P.C.,Serrano-Vega, M.J.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X. (登録日: 2011-03-17, 公開日: 2011-06-01, 最終更新日: 2023-12-20)

• 主引用文献: Moukhametzianov, R.,Warne, T.,Edwards, P.C.,Serrano-Vega, M.J.,Leslie, A.G.,Tate, C.G.,Schertler, G.F.; Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a Beta-1- Adrenergic Receptor.; Proc.Natl.Acad.Sci.USA, 108:8228-, 2011; PubMed: 21540331; DOI: 10.1073/PNAS.1100185108

実験手法

X-RAY DIFFRACTION (3 Å)