2VT4

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL

Summary for 2VT4

Related1DEP 2RH1 2R4R 2R4S
DescriptorBETA1 ADRENERGIC RECEPTOR, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, SODIUM ION, ... (6 entities in total)
Functional Keywordsgpcr, membrane, receptor, palmitate, transducer, antagonist bound form, integral membrane protein, g-protein coupled receptor, g protein coupled receptor, thermostabilising point mutations, phosphoprotein, seven-helix receptor, lipoprotein, 7tm receptor, glycoprotein, transmembrane
Biological sourceMELEAGRIS GALLOPAVO (COMMON TURKEY)
Total number of polymer chains4
Total molecular weight148237.55
Authors
Warne, A.,Serrano-Vega, M.J.,Baker, J.G.,Moukhametzianov, R.,Edwards, P.C.,Henderson, R.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X. (deposition date: 2008-05-09, release date: 2008-06-24, Last modification date: 2013-01-30)
Primary citation
Warne, A.,Serrano-Vega, M.J.,Baker, J.G.,Moukhametzianov, R.,Edwards, P.C.,Henderson, R.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X.
Structure of a Beta1-Adrenergic G-Protein-Coupled Receptor.
Nature, 454:486-, 2008
PubMed: 18594507 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE07101
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers140.5%3.7%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 2vt4
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Molmil generated image of 2vt4
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Molmil generated image of 2vt4
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2vt4.pdb3.gz [49.38 KB])
Coordinate files for Biological unit (2vt4.pdb5.gz [48.03 KB])
Coordinate files for Biological unit (2vt4.pdb4.gz [49.48 KB])
Coordinate files for Biological unit (2vt4.pdb2.gz [92.95 KB])
Coordinate files for Biological unit (2vt4.pdb1.gz [94.62 KB])
Coordinate files for Biological unit (2vt4.pdb6.gz [49.19 KB])
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