2VT4
TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0004935 | molecular_function | adrenergic receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0004935 | molecular_function | adrenergic receptor activity |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0016020 | cellular_component | membrane |
| C | 0004930 | molecular_function | G protein-coupled receptor activity |
| C | 0004935 | molecular_function | adrenergic receptor activity |
| C | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| C | 0016020 | cellular_component | membrane |
| D | 0004930 | molecular_function | G protein-coupled receptor activity |
| D | 0004935 | molecular_function | adrenergic receptor activity |
| D | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| D | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASIeTLCVIAIDRYLaI |
| Chain | Residue | Details |
| A | ALA127-ILE143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 112 |
| Details | TRANSMEM: Helical; Name=1 |
| Chain | Residue | Details |
| A | GLN39-GLY67 | |
| B | GLN39-GLY67 | |
| C | GLN39-GLY67 | |
| D | GLN39-GLY67 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 312 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:18594507 |
| Chain | Residue | Details |
| A | SER68-THR76 | |
| D | SER68-THR76 | |
| D | ASP138-ARG155 | |
| D | ARG232-PHE315 | |
| A | ASP138-ARG155 | |
| A | ARG232-PHE315 | |
| B | SER68-THR76 | |
| B | ASP138-ARG155 | |
| B | ARG232-PHE315 | |
| C | SER68-THR76 | |
| C | ASP138-ARG155 | |
| C | ARG232-PHE315 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 104 |
| Details | TRANSMEM: Helical; Name=2 |
| Chain | Residue | Details |
| A | ASN77-VAL103 | |
| B | ASN77-VAL103 | |
| C | ASN77-VAL103 | |
| D | ASN77-VAL103 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 160 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:18594507 |
| Chain | Residue | Details |
| A | ARG104-GLU115 | |
| D | ARG104-GLU115 | |
| D | HIS180-ARG205 | |
| D | ASN316-VAL320 | |
| A | HIS180-ARG205 | |
| A | ASN316-VAL320 | |
| B | ARG104-GLU115 | |
| B | HIS180-ARG205 | |
| B | ASN316-VAL320 | |
| C | ARG104-GLU115 | |
| C | HIS180-ARG205 | |
| C | ASN316-VAL320 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=3 |
| Chain | Residue | Details |
| A | LEU116-ILE137 | |
| B | LEU116-ILE137 | |
| C | LEU116-ILE137 | |
| D | LEU116-ILE137 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 92 |
| Details | TRANSMEM: Helical; Name=4 |
| Chain | Residue | Details |
| A | ALA156-MET179 | |
| B | ALA156-MET179 | |
| C | ALA156-MET179 | |
| D | ALA156-MET179 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 100 |
| Details | TRANSMEM: Helical; Name=5 |
| Chain | Residue | Details |
| A | ALA206-TYR231 | |
| B | ALA206-TYR231 | |
| C | ALA206-TYR231 | |
| D | ALA206-TYR231 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 116 |
| Details | TRANSMEM: Helical; Name=6 |
| Chain | Residue | Details |
| A | HIS286-PHE315 | |
| B | HIS286-PHE315 | |
| C | HIS286-PHE315 | |
| D | HIS286-PHE315 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 88 |
| Details | TRANSMEM: Helical; Name=7 |
| Chain | Residue | Details |
| A | PRO321-TYR343 | |
| B | PRO321-TYR343 | |
| C | PRO321-TYR343 | |
| D | PRO321-TYR343 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18594507, ECO:0007744|PDB:2VT4 |
| Chain | Residue | Details |
| A | ASP121 | |
| D | ASP121 | |
| D | SER211 | |
| D | ASN329 | |
| A | SER211 | |
| A | ASN329 | |
| B | ASP121 | |
| B | SER211 | |
| B | ASN329 | |
| C | ASP121 | |
| C | SER211 | |
| C | ASN329 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA358 | |
| B | ALA358 | |
| C | ALA358 | |
| D | ALA358 |
