2VT4

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	BETA1 ADRENERGIC RECEPTOR	polymer	313	35752.6	4	UniProt (P07700) Pfam (PF00001)	MELEAGRIS GALLOPAVO (COMMON TURKEY)	BETA-1 ADRENOCEPTOR, BETA-1 ADRENORECEPTOR, BETA-T
2	E, K, P, V (A, B, C, D)	Cyanopindolol	non-polymer		287.4	4	Chemie (P32)
3	F, L, Q, W (A, B, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
4	G, H, I, M, N... (A, B, C, D)	octyl 1-thio-beta-D-glucopyranoside	non-polymer		308.4	12	Chemie (SOG)
5	J, U (A, C)	DECANE	non-polymer		142.3	2	Chemie (D10)
6	AA, BA, CA, DA (A, B, C, D)	water	water		18.0	31	Chemie (HOH)

Sequence modifications

A, B, C, D: 31 - 32 (PDB: 2VT4)
A, B, C, D: 368 - 373 (PDB: 2VT4)
A, B, C, D: 33 - 243 (UniProt: P07700)

PDB	External Database	Details
Ser 68	Arg 68	engineered mutation
Val 90	Met 90	engineered mutation
Leu 116	Cys 116	engineered mutation
Ala 227	Tyr 227	engineered mutation

A, B, C, D: 272 - 276 (UniProt: P07700)
A, B, C, D: 279 - 367 (UniProt: P07700)

PDB	External Database	Details
Leu 282	Ala 282	engineered mutation
Ala 327	Phe 327	engineered mutation
Met 338	Phe 338	engineered mutation
Ala 358	Cys 358	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	143010.4
Non-Polymers*	Number of molecules	22
	Total formula weight	5227.2
All*	Total formula weight	148237.6

*Water molecules are not included.