2VT4
TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | BETA1 ADRENERGIC RECEPTOR | polymer | 313 | 35752.6 | 4 | UniProt (P07700) Pfam (PF00001) In PDB | MELEAGRIS GALLOPAVO (COMMON TURKEY) | BETA-1 ADRENOCEPTOR, BETA-1 ADRENORECEPTOR, BETA-T |
2 | A, B, C, D | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile | non-polymer | 287.4 | 4 | Chemie (P32) | |||
3 | A, B, C, D | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
4 | A, B, C, D | octyl 1-thio-beta-D-glucopyranoside | non-polymer | 308.4 | 12 | Chemie (SOG) | |||
5 | A, C | DECANE | non-polymer | 142.3 | 2 | Chemie (D10) | |||
6 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 31 - 32 (PDB: 2VT4)
A, B, C, D: 368 - 373 (PDB: 2VT4)
A, B, C, D: 33 - 243 (UniProt: P07700)
A, B, C, D: 272 - 276 (UniProt: P07700)
A, B, C, D: 279 - 367 (UniProt: P07700)
A, B, C, D: 368 - 373 (PDB: 2VT4)
A, B, C, D: 33 - 243 (UniProt: P07700)
PDB | External Database | Details |
---|---|---|
Ser 68 | Arg 68 | engineered mutation |
Val 90 | Met 90 | engineered mutation |
Leu 116 | Cys 116 | engineered mutation |
Ala 227 | Tyr 227 | engineered mutation |
A, B, C, D: 279 - 367 (UniProt: P07700)
PDB | External Database | Details |
---|---|---|
Leu 282 | Ala 282 | engineered mutation |
Ala 327 | Phe 327 | engineered mutation |
Met 338 | Phe 338 | engineered mutation |
Ala 358 | Cys 358 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 143010.4 | |
Non-Polymers* | Number of molecules | 22 |
Total formula weight | 5227.2 | |
All* | Total formula weight | 148237.6 |