2Y63

Crystal structure of Leishmanial E65Q-TIM complexed with Bromohydroxyacetone phosphate

2Y63 の概要

• エントリーDOI: 10.2210/pdb2y63/pdb
• 関連するPDBエントリー: 1AMK 1IF2 1N55 1QDS 2VXN 2Y61 2Y62
• 分子名称: TRIOSEPHOSPHATE ISOMERASE, (3-bromo-2-oxo-propoxy)phosphonic acid (3 entities in total)
• 機能のキーワード: isomerase, fatty acid biosynthesis, transition state analogue, glycolysis, pentose shunt, gluconeogenesis, tim, gop, glycosome, lipid synthesis, transition state
• 由来する生物種: LEISHMANIA MEXICANA
• 細胞内の位置: Cytoplasm: P48499
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27441.19

構造登録者

Venkatesan, R.,Alahuhta, M.,Pihko, P.M.,Wierenga, R.K. (登録日: 2011-01-19, 公開日: 2011-12-14, 最終更新日: 2023-12-20)

• 主引用文献: Venkatesan, R.,Alahuhta, M.,Pihko, P.M.,Wierenga, R.K.; High Resolution Crystal Structures of Triosephosphate Isomerase Complexed with its Suicide Inhibitors: The Conformational Flexibility of the Catalytic Glutamate in its Closed, Liganded Active Site.; Protein Sci., 20:1387-, 2011; PubMed: 21633986; DOI: 10.1002/PRO.667

実験手法

X-RAY DIFFRACTION (1.97 Å)