2XUH
CRYSTAL STRUCTURE OF MACHE-Y337A-TZ2PA6 ANTI COMPLEX (10 MTH)
Summary for 2XUH
Entry DOI | 10.2210/pdb2xuh/pdb |
Related | 1C2B 1C2O 1J06 1J07 1KU6 1MAA 1MAH 1N5M 1N5R 1Q83 1Q84 2C0P 2C0Q 2H9Y 2HA0 2HA2 2HA3 2HA4 2HA5 2HA6 2HA7 2JEY 2JEZ 2JF0 2JGE 2JGF 2JGG 2JGH 2JGI 2JGJ 2JGK 2JGL 2JGM 2WHP 2WHQ 2WHR 2WLS 2WU3 2WU4 2XUD 2XUF 2XUG 2XUI 2XUJ 2XUK 2XUO 2XUP 2XUQ |
Descriptor | ACETYLCHOLINESTERASE, 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-4-YL]HEXYL]-PHENANTHRIDINIUM (3 entities in total) |
Functional Keywords | hydrolase, hydrolase fold, click chemistry |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Cellular location | Cell junction, synapse. Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side: P21836 |
Total number of polymer chains | 2 |
Total formula weight | 120668.51 |
Authors | Bourne, Y.,Radic, Z.,Taylor, P.,Marchot, P. (deposition date: 2010-10-19, release date: 2010-12-08, Last modification date: 2023-12-20) |
Primary citation | Bourne, Y.,Radic, Z.,Taylor, P.,Marchot, P. Conformational Remodeling of Femtomolar Inhibitor-Acetylcholinesterase Complexes in the Crystalline State J.Am.Chem.Soc., 132:18292-, 2010 Cited by PubMed: 21090615DOI: 10.1021/JA106820E PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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