2JEY

Mus musculus acetylcholinesterase in complex with HLo-7

Summary for 2JEY

Entry DOI	10.2210/pdb2jey/pdb
Related	1C2B 1C2O 1J06 1J07 1KU6 1MAA 1MAH 1N5M 1N5R 1Q83 1Q84 2C0P 2C0Q 2H9Y 2HA0 2HA2 2HA3 2HA4 2HA5 2HA6 2HA7 2JEZ 2JF0
Descriptor	ACETYLCHOLINESTERASE, 1-[({2,4-BIS[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]-4-CARBAMOYLPYRIDINIUM, HEXAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	acetylcholinesterase, alternative splicing, oxime, mouse, hlo-7, synapse, membrane, hydrolase, neurotransmitter degradation, mus musculus, glycoprotein, serine esterase
Biological source	MUS MUSCULUS (MOUSE)
Total number of polymer chains	2
Total formula weight	121412.95
Authors	Ekstrom, F.,Astot, C.,Pang, Y.P. (deposition date: 2007-01-25, release date: 2007-07-03, Last modification date: 2023-12-13)
Primary citation	Ekstrom, F.J.,Astot, C.,Pang, Y. Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes. Clin.Pharmacol.Ther., 82:282-, 2007 Cited by PubMed: 17443135 DOI: 10.1038/SJ.CLPT.6100151 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation