2JF0

Mus musculus acetylcholinesterase in complex with tabun and Ortho-7

Summary for 2JF0

Entry DOI	10.2210/pdb2jf0/pdb
Related	1C2B 1C2O 1J06 1J07 1KU6 1MAA 1MAH 1N5M 1N5R 1Q83 1Q84 2C0P 2C0Q 2H9Y 2HA0 2HA2 2HA3 2HA4 2HA5 2HA6 2HA7 2JEY 2JEZ
Descriptor	ACETYLCHOLINESTERASE, HEXAETHYLENE GLYCOL, 1,7-HEPTYLENE-BIS-N,N'-SYN-2-PYRIDINIUMALDOXIME, ... (4 entities in total)
Functional Keywords	acetylcholinesterase, alternative splicing, neurotransmitter degradation, hydrolase, mus musculus, glycoprotein, serine esterase, oxime, mouse, tabun, synapse, ortho-7, membrane
Biological source	MUS MUSCULUS (MOUSE)
Total number of polymer chains	2
Total formula weight	121705.37
Authors	Ekstrom, F.,Astot, C.,Pang, Y.P. (deposition date: 2007-01-25, release date: 2007-07-03, Last modification date: 2023-12-13)
Primary citation	Ekstrom, F.J.,Astot, C.,Pang, Y. Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes. Clin.Pharmacol.Ther., 82:282-, 2007 Cited by PubMed: 17443135 DOI: 10.1038/SJ.CLPT.6100151 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation