2HA5

Crystal structure of mutant S203A of acetylcholinesterase complexed with acetylthiocholine

Summary for 2HA5

Entry DOI	10.2210/pdb2ha5/pdb
Related	1J06 2H9Y 2HA0 2HA2 2HA3 2HA4 2HA6 2HA7
Descriptor	Acetylcholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	hydrolase fold, serine esterase, acetylcholinesterase, mutant, homodimer, glycosylated protein, hydrolase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	121778.26
Authors	Bourne, Y.,Radic, Z.,Sulzenbacher, G.,Kim, E.,Taylor, P.,Marchot, P. (deposition date: 2006-06-12, release date: 2006-07-18, Last modification date: 2023-10-25)
Primary citation	Bourne, Y.,Radic, Z.,Sulzenbacher, G.,Kim, E.,Taylor, P.,Marchot, P. Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding J.Biol.Chem., 281:29256-29267, 2006 Cited by PubMed: 16837465 DOI: 10.1074/jbc.M603018200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation