2HA5
Crystal structure of mutant S203A of acetylcholinesterase complexed with acetylthiocholine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 543 | 59748.5 | 2 | UniProt (P21836) Pfam (PF00135) | Mus musculus (house mouse) | AChE |
| 2 | C (C) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 3 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | E, J (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | F, H, K, M, O (A, B) | ACETYLTHIOCHOLINE | non-polymer | 162.3 | 5 | Chemie (AT3) | |||
| 6 | G, I, L, N (A, B) | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL | non-polymer | 120.2 | 4 | Chemie (ETM) | |||
| 7 | P (B) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 8 | Q, R (A, B) | water | water | 18.0 | 886 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 543 (UniProt: P21836)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Ser 234 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119497.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1913.9 | |
| All* | Total formula weight | 121778.3 |
