2WLS

Crystal structure of Mus musculus Acetylcholinesterase in complex with AMTS13

Summary for 2WLS

• Entry DOI: 10.2210/pdb2wls/pdb
• Related: 1C2B 1C2O 1J06 1J07 1KU6 1MAA 1MAH 1N5M 1N5R 1Q83 1Q84 2C0P 2C0Q 2H9Y 2HA0 2HA2 2HA3 2HA4 2HA5 2HA6 2HA7 2JEY 2JEZ 2JF0 2JGE 2JGF 2JGG 2JGH 2JGI 2JGJ 2JGK 2JGL 2JGM 2WHP 2WHQ 2WHR
• Descriptor: ACETYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, N,N,N-trimethyl-13-[(methylsulfonyl)sulfanyl]tridecan-1-aminium, ... (6 entities in total)
• Functional Keywords: serine esterase, alternative splicing, amts13, synapse, membrane, hydrolase, cell membrane, cholinesterase, acetylcholinesterase, neurotransmitter degradation, gpi-anchor, lipoprotein, glycoprotein, cell junction
• Biological source: MUS MUSCULUS (MOUSE)
• Total number of polymer chains: 2
• Total formula weight: 121065.08

Authors

Pang, Y.P.,Ekstrom, F.,Polsinelli, G.A.,Gao, Y.,Rana, S.,Hua, D.H.,Andersson, B.,Andersson, P.O.,Peng, L.,Singh, S.K.,Mishra, R.K.,Zhu, K.Y.,Fallon, A.M.,Ragsdale, D.W.,Brimijoin, S. (deposition date: 2009-06-25, release date: 2009-09-08, Last modification date: 2023-12-13)

• Primary citation: Pang, Y.P.,Ekstrom, F.,Polsinelli, G.A.,Gao, Y.,Rana, S.,Hua, D.H.,Andersson, B.,Andersson, P.O.,Peng, L.,Singh, S.K.,Mishra, R.K.,Zhu, K.Y.,Fallon, A.M.,Ragsdale, D.W.,Brimijoin, S.; Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases.; Plos One, 4:E6851-, 2009; PubMed: 19714254; DOI: 10.1371/JOURNAL.PONE.0006851

Experimental method

X-RAY DIFFRACTION (2.6 Å)