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2XRL

Tet-repressor class D T103A with doxycycline

Summary for 2XRL
Entry DOI10.2210/pdb2xrl/pdb
Related1A6I 1BJ0 1BJY 1BJZ 1DU7 1ORK 1QPI 2TCT 2TRT 2VKE 2VKV 2X6O 2X9D 2XB5 2XGC 2XGD 2XGE 2XPS 2XPT 2XPU 2XPV 2XPW 3ZQF 3ZQG 3ZQH 3ZQI
DescriptorTETRACYCLINE REPRESSOR PROTEIN CLASS D, CHLORIDE ION, (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, ... (5 entities in total)
Functional Keywordstranscription, antibiotic resistance, dna-binding, helix-turn-helix
Biological sourceESCHERICHIA COLI
Total number of polymer chains1
Total formula weight23797.95
Authors
Palm, G.J.,Waack, P.,Hinrichs, W. (deposition date: 2010-09-16, release date: 2011-10-05, Last modification date: 2023-12-20)
Primary citationPalm, G.J.,Buchholz, I.,Werten, S.,Girbardt, B.,Berndt, L.,Delcea, M.,Hinrichs, W.
Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868:140404-140404, 2020
Cited by
PubMed: 32114262
DOI: 10.1016/j.bbapap.2020.140404
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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