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2XRL

Tet-repressor class D T103A with doxycycline

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATETRACYCLINE REPRESSOR PROTEIN CLASS Dpolymer20723258.31UniProt (P0ACT4)
Pfam (PF00440)
Pfam (PF02909)
In PDB
ESCHERICHIA COLI
2ACHLORIDE IONnon-polymer35.52Chemie (CL)
3A(4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDEnon-polymer444.41Chemie (DXT)
4AMAGNESIUM IONnon-polymer24.31Chemie (MG)
5waterwater18.0106Chemie (HOH)
Sequence modifications
A: 3 - 208 (UniProt: P0ACT4)
PDBExternal DatabaseDetails
Ser 2Ala 2cloning artifact
Ala 103Thr 103engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23258.3
Non-Polymers*Number of molecules4
Total formula weight539.6
All*Total formula weight23798.0
*Water molecules are not included.

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PDB entries from 2024-04-24

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