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2XRL

Tet-repressor class D T103A with doxycycline

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
TETRACYCLINE REPRESSOR PROTEIN CLASS Dpolymer20723258.31UniProt (P0ACT4)
Pfam (PF00440)
Pfam (PF02909)
ESCHERICHIA COLI
2B, C
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
3D
(A)
(4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDEnon-polymer444.41Chemie (DXT)
4E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5F
(A)
waterwater18.0106Chemie (HOH)
Sequence modifications
A: 3 - 208 (UniProt: P0ACT4)
PDBExternal DatabaseDetails
Ser 2Ala 2cloning artifact
Ala 103Thr 103engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23258.3
Non-Polymers*Number of molecules4
Total formula weight539.6
All*Total formula weight23798.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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