2XGE

Crystal structure of a designed heterodimeric variant T-A(A)B of the tetracycline repressor

Summary for 2XGE

Entry DOI	10.2210/pdb2xge/pdb
Related	1A6I 1BJ0 1BJY 1BJZ 1DU7 1ORK 1QPI 2TCT 2TRT 2VKE 2VKV 2X6O 2X9D 2XB5 2XGC 2XGD
Descriptor	TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D, 1,2-ETHANEDIOL, SODIUM ION, ... (6 entities in total)
Functional Keywords	chimera, transcription, transcription regulation, antibiotic resistance
Biological source	ESCHERICHIA COLI More
Total number of polymer chains	2
Total formula weight	47276.07
Authors	Stiebritz, M.T.,Wengrzik, S.,Richter, J.P.,Muller, Y.A. (deposition date: 2010-06-03, release date: 2010-09-22, Last modification date: 2023-12-20)
Primary citation	Stiebritz, M.T.,Wengrzik, S.,Klein, D.L.,Richter, J.P.,Srebrzynski, A.,Weiler, S.,Muller, Y.A. Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer. J.Mol.Biol., 403:371-, 2010 Cited by PubMed: 20816982 DOI: 10.1016/J.JMB.2010.07.055 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.14 Å)

Structure validation