2XGE
Crystal structure of a designed heterodimeric variant T-A(A)B of the tetracycline repressor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D | polymer | 208 | 23444.6 | 1 | UniProt (P04483) UniProt (P0ACT4) Pfam (PF00440) Pfam (PF02909) In PDB | ESCHERICHIA COLI | |
2 | B | TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D | polymer | 211 | 23710.9 | 1 | UniProt (P04483) UniProt (P0ACT4) Pfam (PF00440) Pfam (PF02909) In PDB | ESCHERICHIA COLI | |
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 1 - 50 (UniProt: P04483)
A: 51 - 208 (UniProt: P0ACT4)
B: 1 - 50 (UniProt: P04483)
B: 51 - 208 (UniProt: P0ACT4)
A: 51 - 208 (UniProt: P0ACT4)
PDB | External Database | Details |
---|---|---|
Trp 136 | Ala 136 | engineered mutation |
Ala 193 | Leu 193 | engineered mutation |
Ile 197 | Phe 197 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 140 | Phe 140 | engineered mutation |
Trp 192 | Ser 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47155.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 120.5 | |
All* | Total formula weight | 47276.1 |