2XAC
Structural Insights into the Binding of VEGF-B by VEGFR-1D2: Recognition and Specificity
Summary for 2XAC
Entry DOI | 10.2210/pdb2xac/pdb |
Related | 1FLT 1QSV 1QSZ 1QTY 1RV6 2C7W 2VWE |
Descriptor | VASCULAR ENDOTHELIAL GROWTH FACTOR B, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transferase-signaling protein complex, angiogenesis, cysteine-knot protein, mitogen, transferase, signaling protein, transferase/signaling protein |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P49765 Isoform Flt1: Cell membrane; Single-pass type I membrane protein. Isoform sFlt1: Secreted: P17948 |
Total number of polymer chains | 4 |
Total formula weight | 44826.06 |
Authors | Iyer, S.,Darley, P.,Acharya, K.R. (deposition date: 2010-03-30, release date: 2010-05-19, Last modification date: 2023-12-20) |
Primary citation | Iyer, S.,Darley, P.,Acharya, K.R. Structural Insights Into the Binding of Vegf-B by Vegfr-1D2: Recognition and Specificity J.Biol.Chem., 285:23779-, 2010 Cited by PubMed: 20501651DOI: 10.1074/JBC.M110.130658 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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