2WOG

Intermediate and final states of human kinesin Eg5 in complex with S-trityl-L-cysteine

Summary for 2WOG

Related1II6 2FKY 2UYI 1Q0B 2G1Q 2FL6 2GM1 1YRS 2UYM 1X88 2FL2
DescriptorKINESIN-LIKE PROTEIN KIF11, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsatp-binding, motor protein, mitosis, cell cycle, microtubule, cell division, phosphoprotein, nucleotide-binding
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains3
Total molecular weight125611.68
Authors
Kaan, H.Y.K.,Ulaganathan, V.,Hackney, D.D.,Kozielski, F. (deposition date: 2009-07-23, release date: 2010-08-04, Last modification date: 2019-05-15)
Primary citation
Kaan, H.Y.K.,Ulaganathan, V.,Hackney, D.D.,Kozielski, F.
An Allosteric Transition Trapped in an Intermediate State of a New Kinesin-Inhibitor Complex.
Biochem.J., 425:55-, 2010
PubMed: 19793049 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20091207
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22012 1.1% 6.4% 10.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report