1Q0B

Crystal structure of the motor protein KSP in complex with ADP and monastrol

Summary for 1Q0B

Entry DOI	10.2210/pdb1q0b/pdb
Descriptor	Kinesin-like protein KIF11, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	cell cycle, motor protein, monastrol
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P52732
Total number of polymer chains	2
Total formula weight	83336.49
Authors	Yan, Y.,Sardana, V.,Xu, B.,Halczenko, W.,Homnick, C.,Buser, C.A.,Hartman, G.D.,Huber, H.E.,Kuo, L.C. (deposition date: 2003-07-15, release date: 2004-01-13, Last modification date: 2023-08-16)
Primary citation	Yan, Y.,Sardana, V.,Xu, B.,Homnick, C.,Halczenko, W.,Buser, C.A.,Schaber, M.,Hartman, G.D.,Huber, H.E.,Kuo, L.C. Inhibition of a mitotic motor protein: where, how, and conformational consequences J.Mol.Biol., 335:547-554, 2004 Cited by PubMed: 14672662 DOI: 10.1016/j.jmb.2003.10.074 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation