2WMN

Structure of the complex between DOCK9 and Cdc42-GDP.

2WMN の概要

• エントリーDOI: 10.2210/pdb2wmn/pdb
• 関連するPDBエントリー: 1A4R 1AJE 1AM4 1AN0 1CEE 1CF4 1DOA 1E0A 1EES 1GRN 1GZS 1KI1 1KZ7 1KZG 1NF3 1WG7 2ASE 2DFK 2NGR 2WM9 2WMO
• 分子名称: DEDICATOR OF CYTOKINESIS PROTEIN 9, CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: cell cycle, alternative splicing, methylation, prenylation, lipoprotein, coiled coil, gefs, dock9, cdc42, membrane, nucleotide, phosphoprotein, nucleotide-binding, gtp-binding, polymorphism, cell membrane, guanine-nucleotide releasing factor
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): 2WMN
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71646.88

構造登録者

Yang, J.,Roe, S.M.,Barford, D. (登録日: 2009-07-02, 公開日: 2009-09-22, 最終更新日: 2023-12-13)

• 主引用文献: Yang, J.,Zhang, Z.,Roe, S.M.,Marshall, C.J.,Barford, D.; Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor.; Science, 325:1398-, 2009; PubMed: 19745154; DOI: 10.1126/SCIENCE.1174468

実験手法

X-RAY DIFFRACTION (2.391 Å)