2WKO
Structure of metal loaded Pathogenic SOD1 Mutant G93A.
Summary for 2WKO
Entry DOI | 10.2210/pdb2wko/pdb |
Related | 1AZV 1BA9 1DSW 1FUN 1HL4 1HL5 1KMG 1L3N 1MFM 1N18 1N19 1OEZ 1OZT 1OZU 1P1V 1PTZ 1PU0 1RK7 1SOS 1SPD 1UXL 1UXM 2AF2 2C9S 2C9U 2C9V 2V0A 2VR6 2VR7 2VR8 3GZO 3GZP 3GZQ 4SOD |
Descriptor | SUPEROXIDE DISMUTASE [CU-ZN], COPPER (II) ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | amyotrophic lateral sclerosis, phosphoprotein, oxidoreductase, disease mutation, neurodegeneration, acetylation, antioxidant, metal-binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm: P00441 P00441 |
Total number of polymer chains | 2 |
Total formula weight | 32389.87 |
Authors | Antonyuk, S.V.,Galaleldeen, A.,Strange, R.,Whitson, L.,Narayana, N.,Taylor, A.,Schuermann, J.P.,Holloway, S.P.,Hasnain, S.S.,Hart, P.J. (deposition date: 2009-06-16, release date: 2009-11-24, Last modification date: 2023-12-13) |
Primary citation | Galaleldeen, A.,Strange, R.W.,Whitson, L.J.,Antonyuk, S.V.,Narayana, N.,Taylor, A.B.,Schuermann, J.P.,Holloway, S.P.,Hasnain, S.S.,Hart, P.J. Structural and Biophysical Properties of Metal-Free Pathogenic Sod1 Mutants A4V and G93A. Arch.Biochem.Biophys., 492:40-, 2009 Cited by PubMed: 19800308DOI: 10.1016/J.ABB.2009.09.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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