2W97

Crystal Structure of eIF4E Bound to Glycerol and eIF4G1 peptide

2W97 の概要

• エントリーDOI: 10.2210/pdb2w97/pdb
• 関連するPDBエントリー: 1IPB 1IPC 1LJ2 1UG3 2V8W 2V8X 2V8Y
• 分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1, [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE, ... (8 entities in total)
• 機能のキーワード: protein biosynthesis, initiation factor, translation regulation, translation
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 55233.71

構造登録者

Brown, C.J.,Verma, C.S.,Walkinshaw, M.D.,Lane, D.P. (登録日: 2009-01-22, 公開日: 2010-03-31, 最終更新日: 2023-12-13)

• 主引用文献: Brown, C.J.,Verma, C.S.,Walkinshaw, M.D.,Lane, D.P.; Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site.; Cell Cycle, 8:1905-1911, 2009; PubMed: 19440045; DOI: 10.4161/cc.8.12.8742

実験手法

X-RAY DIFFRACTION (2.29 Å)