2VXN

E65Q-TIM complexed with phosphoglycolohydroxamate at 0.82 A resolution

2VXN の概要

• エントリーDOI: 10.2210/pdb2vxn/pdb
• 関連するPDBエントリー: 1AMK 1IF2 1N55 1QDS
• 分子名称: TRIOSEPHOSPHATE ISOMERASE, PHOSPHOGLYCOLOHYDROXAMIC ACID, 2-PHOSPHOGLYCOLIC ACID, ... (6 entities in total)
• 機能のキーワード: isomerase, fatty acid biosynthesis, transition state analogue, glycolysis, pentose shunt, gluconeogenesis, tim, glycosome, triosephosphate isomerase, enzyme-ligand complex, lipid synthesis, transition state, protonation state
• 由来する生物種: LEISHMANIA MEXICANA
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28054.83

構造登録者

Alahuhta, M.,Wierenga, R.K. (登録日: 2008-07-08, 公開日: 2009-07-14, 最終更新日: 2024-05-01)

• 主引用文献: Alahuhta, M.,Wierenga, R.K.; Atomic Resolution Crystallography of a Complex of Triosephosphate Isomerase with a Reaction-Intermediate Analog: New Insight in the Proton Transfer Reaction Mechanism; Proteins, 78:1878-, 2010; PubMed: 20235230; DOI: 10.1002/PROT.22701

実験手法

X-RAY DIFFRACTION (0.82 Å)