2V35

Porcine Pancreatic Elastase in complex with inhibitor JM54

Summary for 2V35

• Entry DOI: 10.2210/pdb2v35/pdb
• Related: 1B0E 1BMA 1BTU 1C1M 1E34 1E35 1E36 1E37 1E38 1EAI 1EAS 1EAT 1EAU 1ELA 1ELB 1ELC 1ELD 1ELE 1ELF 1ELG 1ESA 1ESB 1EST 1FLE 1FZZ 1GVK 1GWA 1H9L 1HAX 1HAY 1HAZ 1HB0 1HV7 1INC 1JIM 1L0Z 1L1G 1LKA 1LKB 1LVY 1MCV 1MMJ 1NES 1OKX 1QGF 1QIX 1QNJ 1QR3 1UO6 1UVO 1UVP 2A7C 2A7J 2BLO 2BLQ 2CV3 2D26 2DE8 2DE9 2EST 2H1U 2V0B 3EST 4EST 5EST 6EST 7EST 8EST 9EST
• Descriptor: ELASTASE-1, (2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID, SODIUM ION, ... (6 entities in total)
• Functional Keywords: serine protease, serine proteases, calcium, zymogen, protease, elastase, hydrolase, inhibition, beta-lactams, metal-binding
• Biological source: SUS SCROFA (PIG)
• Total number of polymer chains: 1
• Total formula weight: 26470.50

Authors

Oliveira, T.F.,Mulchande, J.,Martins, L.,Moreira, R.,Iley, J.,Archer, M. (deposition date: 2007-06-12, release date: 2008-06-24, Last modification date: 2023-12-13)

• Primary citation: Mulchande, J.,Martins, L.,Moreira, R.,Archer, M.,Oliveira, T.F.,Iley, J.; The Efficiency of C-4 Substituents in Activating the Beta-Lactam Scaffold Towards Serine Proteases and Hydroxide Ion.; Org.Biomol.Chem., 5:2617-, 2007; PubMed: 18019537; DOI: 10.1039/B706622H

Experimental method

X-RAY DIFFRACTION (1.67 Å)