1ELE

STRUCTURAL ANALYSIS OF THE ACTIVE SITE OF PORCINE PANCREATIC ELASTASE BASED ON THE X-RAY CRYSTAL STRUCTURES OF COMPLEXES WITH TRIFLUOROACETYL-DIPEPTIDE-ANILIDE INHIBITORS

Summary for 1ELE

Entry DOI	10.2210/pdb1ele/pdb
Related	1ELD
Related PRD ID	PRD_000360
Descriptor	ELASTASE, N-(trifluoroacetyl)-L-valyl-N-[4-(trifluoromethyl)phenyl]-L-alaninamide, CALCIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, serine proteinase, hydrolase/hydrolase inhibitor
Biological source	Sus scrofa (pig)
Cellular location	Secreted: P00772
Total number of polymer chains	1
Total formula weight	26491.51
Authors	Mattos, C.,Petsko, G.A.,Ringe, D. (deposition date: 1994-10-24, release date: 1995-02-14, Last modification date: 2012-12-12)
Primary citation	Mattos, C.,Giammona, D.A.,Petsko, G.A.,Ringe, D. Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors. Biochemistry, 34:3193-3203, 1995 Cited by PubMed: 7880814 DOI: 10.1021/bi00010a008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation