Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin.

Summary for 2UUA

Related1FJG 1GIX 1HNW 1HNX 1HNZ 1HR0 1I94 1I95 1I96 1I97 1IBK 1IBL 1IBM 1J5E 1JGO 1JGP 1JGQ 1L1U 1N32 1N33 1N34 1N36 1PNS 1PNX 1XMO 1XMQ 1XNQ 1XNR 1YL4 2J00 2J02 2UU9 2UUB 2UUC
Descriptor16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... (27 entities in total)
Functional Keywordstrna-binding, rrna-binding, metal-binding, zinc-finger, translation, coiled coil, paromomycin, trna, zinc, mrna, cmo5u, ribosome, rna-binding, modifiactions, ribosomal protein, ribonucleoprotein
Total number of polymer chains23
Total molecular weight796806
Weixlbaumer, A.,Murphy, F.V.,Dziergowska, A.,Malkiewicz, A.,Vendeix, F.A.P.,Agris, P.F.,Ramakrishnan, V. (deposition date: 2007-03-01, release date: 2007-05-15, Last modification date: 2019-02-13)
Primary citation
Weixlbaumer, A.,Murphy 4th., F.V.,Dziergowska, A.,Malkiewicz, A.,Vendeix, F.A.,Agris, P.F.,Ramakrishnan, V.
Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14:498-502, 2007
PubMed: 17496902 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1242
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.25428 5.4% 8.1% 3.5% 0.67MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2uua
no rotation
Molmil generated image of 2uua
rotated about x axis by 90°
Molmil generated image of 2uua
rotated about y axis by 90°