2I16
Human aldose reductase in complex with NADP+ and the inhibitor IDD594 at temperature of 15K
Summary for 2I16
Entry DOI | 10.2210/pdb2i16/pdb |
Related | 1ABN 1ADS 1AZ1 1AZ2 1EF3 1EL3 1IEI 1MAR 1US0 2ACQ 2ACR 2I17 |
Descriptor | Aldose reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, IDD594, ... (5 entities in total) |
Functional Keywords | oxidoreductase, nadp, idd594 |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15121 |
Total number of polymer chains | 1 |
Total formula weight | 37444.25 |
Authors | Petrova, T.,Ginell, S.,Mitshler, A.,Hasemann, I.,Schneider, T.,Cousido, A.,Lunin, V.Y.,Joachimiak, A.,Podjarny, A. (deposition date: 2006-08-13, release date: 2006-08-29, Last modification date: 2023-08-30) |
Primary citation | Petrova, T.,Ginell, S.,Mitschler, A.,Hazemann, I.,Schneider, T.,Cousido, A.,Lunin, V.Y.,Joachimiak, A.,Podjarny, A. Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat. Acta Crystallogr.,Sect.D, 62:1535-1544, 2006 Cited by PubMed: 17139089DOI: 10.1107/S0907444906041035 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.81 Å) |
Structure validation
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