2C5F

Torpedo californica acetylcholinesterase in complex with a non hydrolysable substrate analogue, 4-oxo-N,N,N-trimethylpentanaminium

2C5F の概要

• エントリーDOI: 10.2210/pdb2c5f/pdb
• 関連するPDBエントリー: 1ACJ 1ACL 1AMN 1AX9 1CFJ 1DX6 1E3Q 1E66 1EA5 1EEA 1EVE 1FSS 1GPK 1GPN 1GQR 1GQS 1H22 1H23 1HBJ 1JGA 1JGB 1JJB 1OCE 1ODC 1QID 1QIE 1QIF 1QIG 1QIH 1QII 1QIJ 1QIK 1QIM 1QTI 1SOM 1U65 1UT6 1VOT 1VXO 1VXR 1W4L 1W6R 1W75 1W76 1ZGB 1ZGC 2ACE 2ACK 2C4H 2C58 2C5G 2CEK 2CKM 2CMF 2DFP 3ACE 4ACE
• 分子名称: ACETYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, TRIETHYLENE GLYCOL, ... (6 entities in total)
• 機能のキーワード: hydrolase, serine esterase, synapse, membrane, neurotransmitter cleavage, alpha/beta hydrolase, substrate hydrolysis, michaelis-menten complex, substrate inhibition, alternative splicing, glycoprotein, gpi-anchor, lipoprotein
• 由来する生物種: TORPEDO CALIFORNICA (PACIFIC ELECTRIC RAY)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61935.94

構造登録者

Colletier, J.P.,Fournier, D.,Greenblatt, H.M.,Sussman, J.L.,Zaccai, G.,Silman, I.,Weik, M. (登録日: 2005-10-27, 公開日: 2006-06-14, 最終更新日: 2023-12-13)

• 主引用文献: Colletier, J.P.,Fournier, D.,Greenblatt, H.M.,Stojan, J.,Sussman, J.L.,Zaccai, G.,Silman, I.,Weik, M.; Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase.; Embo J., 25:2746-, 2006; PubMed: 16763558; DOI: 10.1038/SJ.EMBOJ.7601175

実験手法

X-RAY DIFFRACTION (2.6 Å)