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1GQS

ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH NAP

Summary for 1GQS
Entry DOI10.2210/pdb1gqs/pdb
Related1ACJ 1ACL 1AMN 1AX9 1CFJ 1DX6 1E3Q 1E66 1EA5 1EEA 1EVE 1FSS 1GPK 1GPN 1GQR 1HBJ 1OCE 1QID 1QIE 1QIF 1QIG 1QIH 1QII 1QIJ 1QIK 1QIM 1QTI 1SOM 1VOT 1VXO 1VXR 2ACE 2ACK 2DFP 3ACE 4ACE
DescriptorACETYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(1S)-1-(DIMETHYLAMINO)ETHYL]PHENOL, ... (4 entities in total)
Functional Keywordshydrolase, neurotransmitter cleavage, anti-alzheimer drug
Biological sourceTORPEDO CALIFORNICA (PACIFIC ELECTRIC RAY)
Cellular locationIsoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058
Total number of polymer chains1
Total formula weight60801.63
Authors
Bar-on, P.,Millard, C.B.,Harel, M.,Dvir, H.,Enz, A.,Sussman, J.L.,Silman, I. (deposition date: 2001-12-04, release date: 2002-03-15, Last modification date: 2023-12-13)
Primary citationBar-on, P.,Millard, C.B.,Harel, M.,Dvir, H.,Enz, A.,Sussman, J.L.,Silman, I.
Kinetic and Structural Studies on the Interaction of Cholinesterases with the Anti-Alzheimer Drug Rivastigmine
Biochemistry, 41:3555-, 2002
Cited by
PubMed: 11888271
DOI: 10.1021/BI020016X
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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