2BNR

Structural and kinetic basis for heightened immunogenicity of T cell vaccines

2BNR の概要

• エントリーDOI: 10.2210/pdb2bnr/pdb
• 関連するPDBエントリー: 1A1M 1A1N 1A1O 1A6Z 1A9B 1A9E 1AGB 1AGC 1AGD 1AGE 1AGF 1AKJ 1AO7 1B0G 1B0R 1BD2 1CE6 1DE4 1DUY 1DUZ 1E27 1E28 1EFX 1EXU 1FYT 1GZP 1GZQ 1HHG 1HHH 1HHI 1HHJ 1HHK 1HLA 1HSA 1HSB 1I1F 1I1Y 1I4F 1I7R 1I7T 1I7U 1IM3 1IM9 1JF1 1JGE 1JHT 1JNJ 1K5N 1KGC 1KPR 1KTL 1LDS 1OF2 1QLF 1QQD 1QR1 1QRN 1QSE 1QSF 1TMC 2BNQ 2CLR 2HLA 3HLA
• 分子名称: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, BETA-2-MICROGLOBULIN, SYNTHETIC PEPTIDE, ... (6 entities in total)
• 機能のキーワード: immune system/receptor, immune system-receptor-complex, tcr, mhc, immunodominance, flu, complex, transmembrane, glycoprotein, polymorphism, t-cell, receptor, superagonist peptide t-cell vaccines, immune system-receptor complex
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted : P61769; Membrane ; Single-pass membrane protein : 2BNR
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 94102.49

構造登録者

Chen, J.-L.,Stewart-Jones, G.,Bossi, G.,Lissin, N.M.,Wooldridge, L.,Choi, E.M.L.,Held, G.,Dunbar, P.R.,Esnouf, R.M.,Sami, M.,Boultier, J.M.,Rizkallah, P.J.,Renner, C.,Sewell, A.,van der Merwe, P.A.,Jackobsen, B.K.,Griffiths, G.,Jones, E.Y.,Cerundolo, V. (登録日: 2005-03-31, 公開日: 2005-05-23, 最終更新日: 2023-12-13)

• 主引用文献: Chen, J.-L.,Stewart-Jones, G.,Bossi, G.,Lissin, N.M.,Wooldridge, L.,Choi, E.M.L.,Held, G.,Dunbar, P.R.,Esnouf, R.M.,Sami, M.,Boultier, J.M.,Rizkallah, P.,Renner, C.,Sewell, A.,Van Der Merwe, P.A.,Jackobsen, B.K.,Griffiths, G.,Jones, E.Y.,Cerundolo, V.; Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines; J.Exp.Med., 201:1243-, 2005; PubMed: 15837811; DOI: 10.1084/JEM.20042323

実験手法

X-RAY DIFFRACTION (1.9 Å)