2A25

Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP

Summary for 2A25

• Entry DOI: 10.2210/pdb2a25/pdb
• Related: 1k2f 2a26
• Descriptor: Ubiquitin ligase SIAH1, Calcyclin-binding protein peptide, ZINC ION, ... (4 entities in total)
• Functional Keywords: protein-peptide complex, ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q8IUQ4; Nucleus: Q9HB71
• Total number of polymer chains: 2
• Total formula weight: 23013.68

Authors

Santelli, E.,Leone, M.,Li, C.,Fukushima, T.,Preece, N.E.,Olson, A.J.,Ely, K.R.,Reed, J.C.,Pellecchia, M.,Liddington, R.C.,Matsuzawa, S. (deposition date: 2005-06-21, release date: 2005-08-09, Last modification date: 2023-08-23)

• Primary citation: Santelli, E.,Leone, M.,Li, C.,Fukushima, T.,Preece, N.E.,Olson, A.J.,Ely, K.R.,Reed, J.C.,Pellecchia, M.,Liddington, R.C.,Matsuzawa, S.; Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex; J.Biol.Chem., 280:34278-34287, 2005; PubMed: 16085652; DOI: 10.1074/jbc.M506707200

Experimental method

X-RAY DIFFRACTION (2.2 Å)