1K2F
siah, Seven In Absentia Homolog
Summary for 1K2F
Entry DOI | 10.2210/pdb1k2f/pdb |
Descriptor | siah-1A protein, ZINC ION, BETA-MERCAPTOETHANOL, ... (4 entities in total) |
Functional Keywords | beta-sandwich, ligase, protein binding |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm: P61092 |
Total number of polymer chains | 2 |
Total formula weight | 43552.05 |
Authors | Polekhina, G.,House, C.M.,Traficante, N.,Mackay, J.P.,Relaix, F.,Sassoon, D.A.,Parker, M.W.,Bowtell, D.D.L. (deposition date: 2001-09-26, release date: 2001-12-28, Last modification date: 2011-07-13) |
Primary citation | Polekhina, G.,House, C.M.,Traficante, N.,Mackay, J.P.,Relaix, F.,Sassoon, D.A.,Parker, M.W.,Bowtell, D.D. Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling. Nat.Struct.Biol., 9:68-75, 2002 Cited by PubMed: 11742346DOI: 10.1038/nsb743 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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