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1K2F

siah, Seven In Absentia Homolog

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0006511biological_processubiquitin-dependent protein catabolic process
A0007275biological_processmulticellular organism development
A0008270molecular_functionzinc ion binding
B0005737cellular_componentcytoplasm
B0006511biological_processubiquitin-dependent protein catabolic process
B0007275biological_processmulticellular organism development
B0008270molecular_functionzinc ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 601
ChainResidue
ACYS128
ACYS135
AHIS147
AHIS152

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 602
ChainResidue
BCYS128
BCYS135
BHIS147
BHIS152

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 603
ChainResidue
AHIS202
BHIS150
BHIS202
AASP200

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 604
ChainResidue
AHIS230
AGLU269
BHIS230
BGLU269

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 605
ChainResidue
ACYS98
ACYS105
AHIS117
ACYS121

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 606
ChainResidue
BCYS98
BCYS105
BHIS117
BCYS121

site_idAC7
Number of Residues3
DetailsBINDING SITE FOR RESIDUE BME A 550
ChainResidue
ACYS130
APRO131
AILE155

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE BME B 551
ChainResidue
BCYS130
BPRO131
BHIS152
BILE155

site_idAC9
Number of Residues3
DetailsBINDING SITE FOR RESIDUE BME A 552
ChainResidue
AALA222
ACYS282
BARG231

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues120
DetailsZN_FING: SIAH-type => ECO:0000255|PROSITE-ProRule:PRU00455
ChainResidueDetails
ASER93-LYS153
BSER93-LYS153

site_idSWS_FT_FI2
Number of Residues16
DetailsBINDING: BINDING => ECO:0000269|PubMed:11742346, ECO:0000269|PubMed:16615911
ChainResidueDetails
ACYS98
BCYS105
BHIS117
BCYS121
BCYS128
BCYS135
BHIS147
BHIS152
ACYS105
AHIS117
ACYS121
ACYS128
ACYS135
AHIS147
AHIS152
BCYS98

226707

PDB entries from 2024-10-30

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