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2A25

Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitin ligase SIAH1polymer19321693.81UniProt (Q8IUQ4)
Pfam (PF21361)
Pfam (PF03145)
Homo sapiens (human)Seven in absentia homolog 1, Siah-1, Siah-1a
2B
(B)
Calcyclin-binding protein peptidepolymer131254.51UniProt (Q9HB71)CacyBP, hCacyBP, Siah-interacting protein, S100A6-binding protein, PNAS-107
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D, E
(A, B)
waterwater18.0100Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight22948.3
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight23013.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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