2W97
Crystal Structure of eIF4E Bound to Glycerol and eIF4G1 peptide
Summary for 2W97
Entry DOI | 10.2210/pdb2w97/pdb |
Related | 1IPB 1IPC 1LJ2 1UG3 2V8W 2V8X 2V8Y |
Descriptor | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1, [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE, ... (8 entities in total) |
Functional Keywords | protein biosynthesis, initiation factor, translation regulation, translation |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 55233.71 |
Authors | Brown, C.J.,Verma, C.S.,Walkinshaw, M.D.,Lane, D.P. (deposition date: 2009-01-22, release date: 2010-03-31, Last modification date: 2023-12-13) |
Primary citation | Brown, C.J.,Verma, C.S.,Walkinshaw, M.D.,Lane, D.P. Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site. Cell Cycle, 8:1905-1911, 2009 Cited by PubMed: 19440045DOI: 10.4161/cc.8.12.8742 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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